Sitcom, based at CalTech in Pasadena, California. Seeing as how I don't watch TV, I just found out about this show, despite its 2007 debut. I've now watched all the episodes so far, and must nominate this as best sitcom in human history.

*Spoiler from season 3 episode 1*
One of my favourite moments from the series: one of the central characters; Sheldon, a theoretical physicist from Texas conversing with his evangelical mother at her home with his friends watching:
"I will spend the rest of my life here in Texas trying to teach evolution to creationists"
"You watch your mouth Shelly. Everyone's entitled to their opinion."
"Evolution is not opinion it's fact."
"And that is your opinion."
Sheldon turns to friends: "I forgive you lets go home."

Rofl.
*End spoiler*

Anyone else enjoy the show?